We are delighted to announce that AESOP Technology has been awarded
the Silver Prize at the 2024 Taipei Biotech Awards.

​We are deeply grateful for this recognition from the Taipei City Government.

Medication errors are a critical problem in healthcare, and Look-Alike, Sound-Alike (LASA) medication errors pose a particularly daunting challenge. Studies show that LASA errors account for approximately one in four medication errors, making them a significant threat to patients. AESOP Technology is thus pleased to announce remarkable results from its recent clinical research, demonstrating its exceptional effectiveness in preventing LASA errors.

"Accurately identifying LASA errors can be challenging due to their complex origins. Surprisingly, only about 15% of intercepted wrong drug errors during our study could be clearly categorized as LASA errors, in the sense that the medications had similar names that contributed to the mix-up. The LASA errors also did not follow predictable patterns, with only 9 out of 71 cases repeating. These findings underscore the limitations of conventional human-defined rule systems, even when augmented with reinforcement learning. RxPrime (formerly MedGuard) not only detects errors that were not previously identified but also highlights the essential need for AI with advanced medical knowledge, demonstrating a breakthrough in patient safety in healthcare," said Jim Long, CEO of AESOP Technology, explaining the intricacies of detecting medication errors, specifically LASA errors.

AESOP also leverages its proprietary AI technology to overcome the limitations of traditional clinical decision support systems and address the issue of alert fatigue.

"AESOP has taken additional steps to improve problem list documentation to reduce alert fatigue from LASA error detection. Many alerts contributing to physician fatigue result from poor problem list documentation within electronic health record systems. Thus, AESOP intervened at the source by helping physicians complete clinical diagnoses and documentation more effectively while prescribing," Long added.
​
More than half of all medication errors occur during the prescription phase, making it a critical focus for improving patient safety. AESOP's innovative approach offers a beacon of hope. Applying advanced AI technology to this complex problem has yielded impressive results and holds great promise for the healthcare industry. As we address patient safety challenges, AESOP Technology's contributions stand as a testament to the potential of innovative solutions in ensuring the well-being of patients worldwide.

Reference: PR Newswire

SOAP Health's conversational AI for medical encounters, risk and symptom assessment, and documentation integrates with AESOP Technology's electronic medical record data analysis for clinical decision optimization, coding, and productivity.
​
​
BOCA RATON, Fla., Sept. 7, 2023 /PRNewswire/ -- SOAP Health and AESOP Technology are excited to announce a transformative partnership that will push the boundaries of AI-enhanced medical encounters. This collaboration combines AESOP's cutting-edge DxPrime and DeepDRG solutions with SOAP Health's patented and clinically validated Ideal Medical AI Assistant™ to fuse patient-reported data with Electronic Medical Record Systems (EMRs) data to create Precision Patient Profiles™ that give physicians the most comprehensive view and understanding of their patients to improve speed to diagnosis, workflow efficiency, and revenue.

Steven Charlap, MD, MBA, CEO of SOAP Health, believes this alliance marks a milestone in effectively integrating AI into clinical encounters. "By incorporating AESOP's DxPrime into our existing solutions, we are elevating the realm of data-driven clinical decision-making. DxPrime's DeepDRG and Natural Language Processing capabilities are revolutionary, enhancing the quality and efficiency of data analysis and diagnostic decisions," said Dr. Charlap. "Combined with SOAP's patented and clinically validated Ideal Medical AI Assistant™, this partnership promises to enhance medical encounters, providing a robust, integrated solution that is unparalleled in today's market."

Combined with SOAP's integration with Dolbey Fusion Narrate™, a previously announced partnership, the Precision Patient Profile™ will seamlessly integrate into over 100 EMRs, fortifying the power of these applications to deliver value to physicians. "The joint venture between AESOP Technology and SOAP Health promises to radically optimize physician data collection and medical coding," says Jeremiah Scholl, Co-founder and CPO of AESOP Technology. "Our shared mission is to harness the power of AI to improve patient outcomes and clinical efficiency, and this partnership is a giant leap toward fulfilling that commitment."

SOAP Health's vision to reduce diagnostic errors aligns perfectly with AESOP's focus on improving the quality and efficiency of clinical decision-support and medical coding. This partnership is poised to bring significant advancements in physician practice, optimizing patient care and safety.
For more details on how SOAP Health and AESOP Technology are collaborating, please visit the SOAP Health Partner Page at www.soap.health/aesop

About AESOP Technology
AESOP Technology harnesses advanced AI to improve the clinical decision-making process, enhance medical coding quality, and prioritize patient safety. AESOP's flagship products, DxPrime and DxCode, boast 99% accuracy in identifying and analyzing data and integrate directly into physicians' clinical workflows. DeepDRG is the unique AI approach they developed to unlock understanding of how diagnoses are typically associated with structured clinical data like lab results, medications, and procedures. To learn more about AESOP Technology, visit aesoptek.com.

About SOAP Health
SOAP Health is a trailblazer in medical practice AI. Through patented conversational and generative AI, SOAP's mission is to save lives by reducing diagnostic errors, accounting for over 800,000 preventable deaths and permanent disabilities each year. The company leverages the collective expertise of seasoned medical entrepreneurs, scientists, and technologists to deliver clinically validated solutions. To learn more about SOAP Health, visit soap.health. 

AESOP Technology, in collaboration with AstraZeneca Taiwan, has unveiled Medigator, an innovative AI software designed to manage immune-related adverse events (irAEs) and enhance the effectiveness of immunotherapy. With cancer being the second leading cause of death and immunotherapy offering improved survival rates, Medigator is specially designed to address the potential challenges associated with irAEs that may deter some patients from choosing this treatment.

The American Cancer Society estimates that of the 2 million new cancer cases in the U.S. in 2023, about half could be eligible for immunotherapy treatment. While this treatment stimulates the patient's immune system to fight cancer, it can potentially trigger an overactive immune response, leading to irAEs.
Managing irAEs is challenging due to the unique immune responses and variability in the reaction to immunotherapy. The intensified immune response that fights cancer cells can inadvertently harm normal tissues. Effective communication is crucial to educate patients about possible side effects, readiness for assistance, and timely medical intervention. Mild irAEs can often be managed symptomatically with topical treatments, while severe cases may require discontinuing immunotherapy and administering immune-suppressing medications.

To address the complexities of managing irAEs, Medigator offers real-time assistance to physicians. This tool manages the risk of irAEs and is seamlessly integrated into the Computerized Physician Order Entry system.
"By harnessing the power of big data analytics, Medigator analyzes real-world patient experiences with irAEs, physicians' management strategies, and patient responses to treatment based on a dataset of 197,921 claim-based prescriptions. Using these analytical parameters, Medigator goes a step further by predicting the risk levels of different irAEs in individual patients. It provides personalized medication options by considering factors such as patient age, gender, race, chronic medical conditions, and genetic history, empowering physicians to enhance their risk management strategies in the care plan," explained Jim Long, CEO of AESOP Technology.

"Medigator is an immunotherapy medication navigator designed for physicians. It aims to minimize interruptions in immunotherapy, preserve valuable treatment time and resources, and alleviate the treatment burden," said Jim Long.

"The origin of the partnership between AESOP Technology and AstraZeneca Taiwan traces back to 2019 at an international biomedical accelerator co-hosted by AstraZeneca A.Catalyst Network and the National Biotechnology Research Park in Taiwan, which is dedicated to exploring new possibilities to change patients' lives. Medigator has set a promising example demonstrating patient-centric innovation by advancing shared decision-making in precision medicine," said Ben Chen, Medical Director, AstraZeneca Taiwan.

The research findings of Medigator, which were recently presented at the annual meeting of the American Society of Clinical Oncology, received notable attention. AESOP Technology continues its unwavering commitment to delivering physicians with precise and personalized solutions for irAEs as immunotherapy advances. Its ultimate goal is to enhance immunotherapy treatment outcomes and improve patients' overall quality of life.

Reference
Yahoo Finance

Digital health startup AESOP Technology has raised a $2.95 million series pre-A round to address the growing medical and billing errors problem. The round was led by Taiwania Capital with participation from Colopl Next, 500 Startups, and BE Capital.

Originally from Taiwan, AESOP started as a university spin-off from Taipei Medical University (TMU). Professor Yu Chuan (Jack) Li, the founder and current president of the International Medical Informatics Association, spent ten years before AESOP working on big data approaches to reduce medication errors. He initially applied the model to launch a product, RxPrime (previously known as MedGuard), that identifies wrong-drug errors.

During the pandemic in 2020, Prof. Li officially established AESOP in the US with his former student, who grew to become CIO of a TMU-affiliated hospital, Dr. Jim Long, and former TMU Visiting Assistant Professor, Dr. Jeremiah Scholl. They worked together to broaden the types of errors the AI could identify and on products they could use to improve the US healthcare system.

"Our solution is revolutionary and generalizable." CEO Jim Long described. "We have developed an AI model with an exceptional understanding of the association between diagnoses and structured clinical data like medications, lab results, and procedures."

One of the first errors RxPrime identified was a 9-year-old girl accidentally prescribed an anti-schizophrenia drug for simple back pain. Another commonly prescribed error was Acetaminophen (pain killer), sometimes mistaken as Acetazolamide (glaucoma and altitude illness). "These mistakes might occur just because the two drugs have look-alike or sound-alike (LASA) names. It is horrible to think about, but errors like LASA happen in hospitals everywhere." Jim explained

By tweaking the model developed for RxPrime, they quickly launched a second product, DxPrime, focusing on diagnosis errors. "Launching AESOP when the pandemic was outbreaking also made us think about using AI to save physicians time and reduce burnout." CPO Jeremiah Scholl said. "Instead of only flagging errors, we can also use it to clarify the proper diagnosis and remind missing ones.
When diagnosing, physicians need to consider many factors simultaneously and then select the related and unique code from the 68,000-diagnosis code list. However, hospital information systems are more designed to support medical billing than clinical decision-making. "With DxPrime, we directly display all the plausible proper diagnoses to the physicians to consider, help them keep focused on what matters without wasting time searching or getting bothered later to fix it."

DxPrime has achieved 100% user adoption based on extensive experience in physician-centric clinical decision support systems, and its solutions have been approved to be clinically relevant. Helping physicians efficiently select the correct diagnostic code also results in more accurate billing. AESOP claims that the first few hospitals using DxPrime have seen a 5% increase in reimbursement per inpatient and fewer denials from insurance companies.

The fact that various venture capital investors from the US, Japan, and Taiwan participated in AESOP's pre-A fundraising demonstrates the importance that the international community places on the advancement of medical technology. AESOP can also connect different local resources and business relationships for international expansion by seizing this opportunity.
​
AESOP will use the funding to secure their push into the US market and strengthen the tech team. This push follows them moving their headquarters to San Francisco, launching two apps in the Epic App Market, being accepted into the Mayo Clinic Platform_Accelerate, and publishing a paper with Harvard University last year demonstrating the portability of their model at US hospitals.

Reference: PR Newswire

AESOP Technology announced that they have been accepted into Mayo Clinic Platform_Accelerate, a 20-week program that helps early-stage health tech AI startups get market-ready.

Participants are selected through a competitive screening process where a panel of Mayo Clinic leaders reviews them from the clinical and operational perspective, led by John Halamka, MD., President of Mayo Clinic Platform.

"It's an excellent opportunity for a medical AI startup like us. Data is the fuel from which everything grows into power, and this program provides de-identified patient datasets and tools to help us validate our solutions," says Jeremiah Scholl, the CPO of AESOP Technology. "This practical experience will help us go even further in developing better products. The fact that we get to be mentored by Mayo Clinic's reputable experts is inspiring."

'AESOP',  which stands for 'AI-Enhanced Safety of Prescription', is working to make physician data entry easier, faster, and less error-prone using machine learning on 3.2 billion data sets. The company has developed products capable of this. One is RxPrime which detects wrong drug errors by checking if medications match patients' diagnoses, age, and gender.

Errors can happen at any stage of the medication-use process, but more than 50% of them occur during the prescribing phase. RxPrime is able to detect potential and unexplained errors in prescriptions and provide optimal recommendations, even for the look-alike-sound-alike medication errors. It offers just-in-time decision support without interfering unnecessarily with the clinical consultation process.

The other is AESOP Technology's latest clinical documentation improvement tool, DxPrime, making it easier for doctors to input correct diagnoses into electronic health record systems. This task can be challenging as there are 68,000 different diagnosis codes under the International Classification of Diseases (ICD). The ICD codes were designed to support insurance and billing rather than clinical medicine.

"Medical professionals are more overwhelmed with their workload after the pandemic. How AI can support them gains more importance," says Jim Long, the CEO of AESOP Technology. "AI is transforming the healthcare industry in a variety of ways, like any other industry. Healthcare has unique challenges, and this program will help us be more grounded."
​
As a participant of the Mayo Clinic Platform_Accelerate, AESOP Technology is glad to expose themselves to real-world applications, which helps cultivate future growth in this rapidly progressing field.  As part of the program, Mayo Clinic will take an equity position in the startup.

Reference: HEALTHCARE REPORT

ROCHESTER, Minn. — Mayo Clinic Platform_Accelerate has announced its second cohort of health tech startups, including national and international businesses. The program will help seven companies develop and validate their artificial intelligence-driven health care products or solutions and advance their business plans.

The immersive, 20-week program offers participants access to Mayo Clinic experts in regulatory, clinical, technology and business domains with a focus on AI model validation and clinical readiness. Technology experts from Google and Epic also will provide workshops for the participants.

"The only way we can transform health care is by bringing together clinical experts with technology innovators," says John Halamka, M.D., president of Mayo Clinic Platform, a strategic initiative to improve health care through insights and knowledge derived from data.

"Our Accelerate program combines emerging companies with breakthrough ideas, leaders from Mayo's clinical practice and our unique 'data behind glass' approach to algorithm development," Dr. Halamka says, describing the secure environment that allows companies to build algorithm models they can use for innovation, but the data never leave the Mayo Clinic Platform.
​
The program will help participants explore ways to improve health care in a variety of areas:

• AESOP Technology: Using machine learning on 3.2 billion patient visits, AESOP aims to make physician data entry easier, faster and less error-prone by automating diagnosis input and improving medication-related workflows. AESOP has offices in California, Colorado and Taiwan.

• Biotia: By fighting infectious diseases with AI and genomics, Biota is leveraging new DNA sequencing technology to enable personalized, data-driven discovery of microorganisms that cause illness. The company is based in New York City.

• Delfina: Tackling the maternal health crisis, Delfina’s software is monitoring health data to assess pregnancy risks, coordinate with providers and deliver a personalized care plan to improve pregnancy outcomes. Delfina has offices in San Francisco, New York City and Rochester, Minnesota.

• Dynocardia: Using wearable technology for accurate real-world continuous blood pressure and other advanced heart function measures, Dynocardia is leveraging AI to enable early detection before serious health events. The company is based in Cambridge, Massachusetts.

• ImpriMed: To personalize human and animal cancer treatment, ImpriMed aims to validate an oncology platform to provide patients and clinicians with the best predictive information for individual cancer patients. The company has offices in Palo Alto, California, and Seoul, South Korea.

• Predicta Med: To shorten the diagnostic journey and enable early and effective treatment, Predicta Med is creating an AI-based decision support platform for early detection of autoimmune diseases. The company is based in Tel Aviv, Israel.

• SOAP Health: SOAP (Subjective, Objective, Assessment, Plan) Health seeks to enhance physician productivity and insight to ensure accurate and timely prediagnosis — made before occurrence of symptoms — and diagnosis. The company is based in Boca Raton, Florida.

Chosen from a competitive process, each company receives a benefit package that offers:

• Access to deidentified patient data in a secure environment.
• AI model validation with guidance from data science experts.
• Ability to check for fairness and bias in AI models.
• Exploratory collaboration discussions with clinical experts.
• Guidance to understand Food and Drug Administration clearance pathways.
• Support to plan clinical validation studies, such as clinical simulation or clinical research trials.

As part of this in-kind investment, Mayo Clinic Platform will have an equity position in the companies.
​
"In our first cohort, we already have seen these companies receive attention from potential investors, health care providers and others who want to support their work," says Eric Harnisch, vice president, Partner Programs, Mayo Clinic Platform. "We are excited to further these efforts with the second group of companies."

The inaugural cohort of four companies recently finished the program. Applications for the third Mayo Clinic Platform_Accelerate cohort will be open soon and reviewed on a rolling basis.

About Mayo Clinic Platform
Founded on Mayo Clinic’s dedication to patient-centered care, Mayo Clinic Platform. enables new knowledge, new solutions and new technologies through collaborations with health technology innovators to create a healthier world. To learn more, visit Mayo Clinic Platform.

About Mayo Clinic
Mayo Clinic is a nonprofit organization committed to innovation in clinical practice, education and research, and providing compassion, expertise and answers to everyone who needs healing. Visit the Mayo Clinic News Network for additional Mayo Clinic news.

Reference: Mayo Clinic